<div dir="ltr"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;text-align:center;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><span style="border:none;display:inline-block;overflow:hidden;width:602px;height:301px"><br class="gmail-Apple-interchange-newline"><img src="https://lh3.googleusercontent.com/p-zDeFPYkVJFqLDQjRuu9L0U4nO8OqGGcrsziD9U5rnAgUyIFiUOIXHDpsL4TiX_09JzVCnUolJh4VWialc1klbwqB4IIqd3ewjvV5D3SFd3ZDy5vVUEUdQwC8c9rif9v-cIcJ2CQLiJpkgrguSeahM" width="602" height="301" style="margin-left: 0px; margin-top: 0px;"></span></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">reply-to: </span><a href="mailto:elixirit.tp.bari@gmail.com" style="text-decoration:none"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;text-decoration:underline;vertical-align:baseline;white-space:pre-wrap">elixirit.tp.bari@gmail.com</span></a></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>COURSE ANNOUNCEMENT</b></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Please circulate this email to those who might be interested.</span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">ELIXIR-IIB, in collaboration with the University of Bari, Italy,  and the support of IBIOM-CNR and IIT,</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">is pleased to announce the upcoming “Training course in computational methods for epitranscriptomics”.</span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>IMPORTANT DATES:</b></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Deadline for applications: </span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-weight:700;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">15 April 2023</span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><br></span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Course date:</span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-weight:700;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"> 26-28 April 2023</span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><br></span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Acceptance will be notified soon after the registration deadline</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Course selection will be done according to the needs for the course as emerging from the application form. </span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Priority will be given to candidates from ELIXIR-IT member institutions (see the </span><a href="https://elixir-italy.org/about/members/" style="text-decoration:none"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;text-decoration:underline;vertical-align:baseline;white-space:pre-wrap">list</span></a><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">) and ELIXIR nodes. </span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>VENUE:</b></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Area della Ricerca del CNR di Bari </span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Via Amendola 122/o, 70126 Bari, Italy</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><a href="https://www.ba.cnr.it/dovesiamo.html" style="text-decoration:none"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;text-decoration:underline;vertical-align:baseline;white-space:pre-wrap">https://www.ba.cnr.it/dovesiamo.html</span></a></p><br style="color:rgb(0,0,0)"><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>FEE: </b>The course is free of charge.</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Coffee breaks and lunch are offered. Travel, accommodation and additional meals are not included. </span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Full details at: </span><a href="https://elixir-iib-training.github.io/website/2023/04/26/Computational_Methods_for_Epitrascriptomics_Bari.html" style="text-decoration:none"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;text-decoration:underline;vertical-align:baseline;white-space:pre-wrap">https://elixir-iib-training.github.io/website/2023/04/26/Computational_Methods_for_Epitrascriptomics_Bari.html</span></a></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>COURSE DESCRIPTION:</b></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">The aim of the course is to provide a foundation on experimental planning, analytical strategies, and computational approaches for using RNAseq and Nanopore direct RNA sequencing to profile RNA modifications. Participants will learn the fundamental concepts and bioinformatics skills needed for epitranscriptome analysis, and acquire specific skills in command-line tools for calling, annotating and filtering RNA variants. The course also covers theoretical aspects of RNA editing and practical sessions focused on its detection in human/mouse transcriptomes using Illumina RNAseq data.</span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><b>COURSE TOPICS:</b></span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap"><br></span><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">- Theoretical aspects of Nanopore direct RNA sequencing to profile RNA modifications;</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">- Hands on bioinformatics tools for the analysis of Nanopore direct RNA sequencing data;</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">- Theoretical aspects of computational methods to detect RNA editing in human/mouse transcriptomes using Illumina RNAseq data.</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">- Hands on bioinformatics tools for calling, annotating and filtering RNA editing events.</span></p><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Should you have any question, do not hesitate to contact the course Local Organizers (<a href="mailto:elixirit.tp.bari@gmail.com">elixirit.tp.bari@gmail.com</a>)</span></p><br style="color:rgb(0,0,0)"><br style="color:rgb(0,0,0)"><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="font-size:10pt;font-family:&quot;Times New Roman&quot;;font-variant-ligatures:normal;font-variant-numeric:normal;font-variant-alternates:normal;font-variant-east-asian:normal;vertical-align:baseline;white-space:pre-wrap">Thank you for your interest,</span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="border:none;display:inline-block;overflow:hidden;width:184px;height:65px"><span style="font-family:&quot;Times New Roman&quot;;font-size:13.333333px;white-space:pre-wrap">The Organisers</span></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><span style="border:none;display:inline-block;overflow:hidden;width:184px;height:65px"><img alt="logo_iib.png" src="https://lh5.googleusercontent.com/1PHwUX-l4D4xhAQ10nuLeVNshTen9mYaWZLXqRSVFYvGa5sAu83imNsrBdiSDd7q3uOYjJ8zQrwKNxzQ3p96NxDS1uzbcrQBvFpJnX8FSPkU-mUzbcaQW7W-wS-gL_jaPzpeouGRGMC6Gvkl_1CgZIg" width="184" height="65" style="margin-left: 0px; margin-top: 0px;"></span></p><p dir="ltr" style="color:rgb(0,0,0);line-height:1.38;margin-top:0pt;margin-bottom:0pt"><br></p><br style="color:rgb(0,0,0)"><br style="color:rgb(0,0,0)"><br style="color:rgb(0,0,0)"></div>